Joakim Lundeberg

Oct 16, 2024 | dailyreporter.esmo.org | Joakim Lundeberg

For many decades, our understanding of the spatial biology of tumours came only from microscopy, for example, using immunohistochemistry to identify specific proteins within a tumour section. However, advances in spatial transcriptomics technology mean that we can now pinpoint which genes are active within different parts of the tumour and its microenvironment.

Oct 16, 2024 | dailyreporter.esmo.org | Joakim Lundeberg

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Jul 23, 2024 | nature.com | Joakim Lundeberg

AbstractSolid tumours comprise many different cell types organized in spatially structured arrangements, with substantial intratumour and intertumour heterogeneity. Advances in spatial profiling technologies over the past decade hold promise to capture the complexity of these cellular architectures to build a holistic view of the intricate molecular mechanisms that shape the tumour ecosystem.