
John Kollins
Articles
Relationship of dihydroergotamine pharmacokinetics, clinical efficacy, and nausea-A narrative review
Nov 27, 2024 |
headachejournal.onlinelibrary.wiley.com | Richard Lipton |John Kollins |Detlef Albrecht
2hPR 2-h pain relief 5-HT 5-hydroxytryptamine AUC area under the concentration–time curve C max maximum plasma concentration DHE dihydroergotamine PD pharmacodynamics PK pharmacokinetics RCT randomized controlled trial T max time to peak concentration INTRODUCTION Migraine is a common primary headache disorder contributing to significant long-term disability and manifesting in attacks of moderate to severe pulsating unilateral pain with nausea, photophobia, and phonophobia in various...
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