John Riley

Jun 17, 2024 | jci.org | John Riley |Valerie L. Luks |Ana Maria Dumitru |Cara L. Berkowitz

AbstractIn utero gene editing (IUGE) is a potential treatment for inherited diseases that cause pathology before or soon after birth. Preexisting immunity to adeno-associated virus (AAV) vectors and Cas9 endonuclease may limit postnatal gene editing. The tolerogenic fetal immune system minimizes a fetal immune barrier to IUGE. However, the ability of maternal immunity to limit fetal gene editing remains a question. We investigated whether preexisting maternal immunity to AAV or Cas9 impairs IUGE.

Apr 19, 2024 | kpax.com | Allie Kaiser |John Riley

HELENA — According to the Original Montana Club Cooperative Association, a prospective buyer has signed a contract to purchase the historic Montana Club. Announced Friday, businessman and software entrepreneur Ajitpal Pannu has entered into a $1.3 million agreement to buy the entire Montana Club operations, the liquor license, the club-owned floors of the building, the Rathskeller, and all furniture and equipment. “I invest in three things.

Apr 2, 2024 | dataweek.co.za | John Riley

Editor's Choice printer friendly versionWhat is an RF connector? To understand an RF connector, we first need to look at RF signals. An RF (radio frequency) signal refers to an alternating current (AC) signal characterised by its frequency falling within the radio frequency range. This typically includes frequencies from 3 kHz to 300 GHz. RF signals are widely used in various communication systems, such as radio broadcasting, television, wireless communication, and radar.

May 20, 2023 | biorxiv.org | John Riley

Jun 27, 2022 | ktvq.com | John Riley