Joji Teves

Nov 25, 2024 | biorxiv.org | Adam M Beitz |Conrad G. Oakes |Christopher Johnstone |Joji Teves

AbstractWhile transcription factors (TFs) provide essential cues for directing and redirecting cell fate, TFs alone are insufficient to drive cells to adopt alternative fates. Rather, transcription factors rely on receptive cell states to induce novel identities. Cell state emerges from and is shaped by cellular history and the activity of diverse processes.