Jonathan Benn

Aug 29, 2024 | science.org | Sara Martin |Melody Di Bona |Michael P. Fatt |Jonathan Benn

Editor’s summaryProtein aggregates are the major cause of neuronal death in many neurodegenerative disorders. However, in the nonaggregate form, the same proteins play important physiological roles. Benn et al. developed a strategy to target intracellular protein aggregates while sparing the monomeric form. Exploiting the clustering-dependent activation of TRIM21, the authors generated degraders combining the RING domain of TRIM21 with a target-specific nanobody.

Sep 19, 2023 | qualitysafety.bmj.com | Caitlin Wilson |Gillian Janes |Rebecca Lawton |Jonathan Benn

Prehospital careAudit and feedbackHealth services researchDecision makingData availability statementAll data relevant to the study are included in the article or uploaded as supplementary information.

Aug 9, 2023 | mdpi.com | Gillian Janes |Rebecca Lawton |Jonathan Benn |Caitlin Wilson

Dear Colleagues,Pre-hospital care is an important component of health systems, traditionally consisting of emergency medical services providing emergency treatment and conveying patients to emergency departments. The role of pre-hospital healthcare provision has rapidly evolved in recent decades.

Aug 8, 2023 | mdpi.com | Caitlin Wilson |Gillian Janes |Rebecca Lawton |Jonathan Benn

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Apr 7, 2023 | qualitysafety.bmj.com | Caitlin Wilson |Gillian Janes |Rebecca Lawton |Jonathan Benn

Feedback intervention types and designs within EMS (interventional studies)The interventional studies (n=42) described 37 unique EMS feedback interventions. Sources of feedback included researchers (n=17, 40%), ambulance service managers (n=14, 33%), peers (n=6, 14%) and external databases (n=1, 2%). Feedback was provided to organisations (n=8, 19%), ambulance crews/teams (n=16, 38%), individual clinicians (n=10, 24%) or a combination (n=7, 17%).