Jonathan Kipnis

Aug 3, 2024 | flipboard.com | Jonathan Kipnis

Opinion (Canada)5 hours agoBrownstein: Sales sizzle for Montreal hot-sauce maker after endorsement by sweating film starsmontrealgazette.com - Bill Brownstein, Montreal Gazette • 5hSome may think Mark Cregan is in the colonics trade. Australia10 hours agoHunter, 14, was sent home from hospital twice.

Jul 31, 2024 | nature.com | Celia Dobersalske |Laurèl Rauschenbach |Yichao Hua |Christoph Alexander Berliner |Anika Grüneboom |Dieter H. Heiland | +12 more

AbstractThe ecosystem of brain tumors is considered immunosuppressed, but our current knowledge may be incomplete. Here we analyzed clinical cell and tissue specimens derived from patients presenting with glioblastoma or nonmalignant intracranial disease to report that the cranial bone (CB) marrow, in juxtaposition to treatment-naive glioblastoma tumors, harbors active lymphoid populations at the time of initial diagnosis.

Jul 31, 2024 | nature.com | Celia Dobersalske |Laurèl Rauschenbach |Yichao Hua |Christoph Alexander Berliner |Anika Grüneboom |Dieter H. Heiland | +12 more

AbstractThe ecosystem of brain tumors is considered immunosuppressed, but our current knowledge may be incomplete. Here we analyzed clinical cell and tissue specimens derived from patients presenting with glioblastoma or nonmalignant intracranial disease to report that the cranial bone (CB) marrow, in juxtaposition to treatment-naive glioblastoma tumors, harbors active lymphoid populations at the time of initial diagnosis.

Jul 25, 2024 | science.org | Giulia Santoni |Natalia Condic |Alice-Agnes Gabriel |Jonathan Kipnis

Lymphatic drainage removes metabolic waste and toxins from tissues, which is crucial for maintaining tissue health. In the central nervous system (CNS), lymphatic drainage relies on meningeal lymphatic vessels located in the dura mater and on the glymphatic system, a recently elucidated network that is responsible for cerebrospinal fluid (CSF) circulation and waste clearance.

Apr 9, 2024 | cell.com | Jonathan Kipnis

Highlights‘Neuroinflammation’, one of the hallmarks of many neurodegenerative diseases, causes inadvertent damage to neuronal tissue due to the immune system’s response to the underlying pathology. The role of the immune system in the development and progression of many neurodegenerative diseases remains elusive, with conflicting evidence in similar model systems.