Jose A. Karam

Oct 29, 2024 | mdanderson.org | Jose A. Karam

Orchiectomy — also known as orchidectomy — is the scientific term for the surgical removal of a testicle. It is usually performed to treat and confirm a diagnosis of testicular cancer, though it may be done for other reasons. If you’ve been told that you need this procedure, you might have some concerns. Does an orchiectomy hurt? How will it change the way your body looks and functions? Will you still be able to have sex and father children? Here is what I tell my patients about orchiectomies.

Sep 16, 2024 | brnw.ch | Jose A. Karam

Kidney cancers don’t generally cause pain in patients before diagnosis. That’s because the most common types of kidney cancer tend to grow very slowly, so they gently push other organs aside as they get larger. But what does kidney cancer pain feel like? And what causes the rest of the sensations people often describe as “kidney pain?” Read on to find out.

Sep 6, 2024 | digitalcommons.library.tmc.edu | Jose A. Karam |Pavlos Msaouel |Cara Haymaker |Surena F. Matin

Sitravatinib is an immunomodulatory tyrosine kinase inhibitor that can augment responses when combined with programmed death-1 inhibitors such as nivolumab. We report a single-arm, interventional, phase 2 study of neoadjuvant sitravatinib in combination with nivolumab in patients with locally advanced clear cell renal cell carcinoma (ccRCC) prior to curative nephrectomy (NCT03680521).

Mar 5, 2024 | medscape.com | Jose A. Karam

closePlease confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Jose A. Karam, MD, discusses the challenges faced by patients with lower socioeconomic status and living in poorer communities when it comes to timely diagnosis and treatment of diseases like renal medullary carcinoma (RMC), a rare form of renal cell carcinoma that predominantly affects young African American men.

Mar 5, 2024 | medscape.com | Jose A. Karam

closePlease confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Jose A. Karam, MD, strongly urges early career clinicians, particularly urology or medical oncology residents and fellows, to seek mentorship as soon as possible, even beyond training. Having multiple mentors from various aspects of kidney cancer care is crucial for comprehensive development.