Joseph F Standing

Mar 20, 2024 | ascpt.onlinelibrary.wiley.com | Qi Liu |Amita Joshi |Joseph F Standing

In recent years, artificial intelligence (AI) and machine learning (ML) have emerged as transformative forces driving innovation across various sectors. This themed issue of Clinical Pharmacology & Therapeutics (CPT) is dedicated to AI/ML Innovations (Figure 1), showcasing a wide range of opportunities for applying these technologies in clinical pharmacology.

Feb 23, 2024 | nature.com | Joseph F Standing |Laura Buggiotti |Claire Smith |Theo Sanderson |Fiona Ashford |Adrian Shields | +13 more

AbstractViral clearance, antibody response and the mutagenic effect of molnupiravir has not been elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 symptoms randomised to receive molnupiravir (n = 253) or Usual Care (n = 324) were recruited to study viral and antibody dynamics and the effect of molnupiravir on viral whole genome sequence from 1437 viral genomes. Molnupiravir accelerates viral load decline, but virus is detectable by Day 5 in most cases.