Jules Ross

Jul 30, 2024 | onlinelibrary.wiley.com | Jules Ross |Stephanie Forte |Nicolas Mercure-Corriveau |Anne-Sophie Lemay

INTRODUCTION Approximately 20% of adults with sickle cell anaemia (HbSS and HbSβ0) rely on chronic blood transfusions as part of their disease management,1 often in the form of automated or manual red blood cell exchange (RCE) in accordance with current guidelines for transfusion support in sickle cell disease (SCD).2 The former technique involves replacing native red blood cells (RBC) with multiple donor RBC units per procedure to reach the desired fraction of cells remaining (FCR) while...