Julia Enterria-Rosales

Jan 17, 2025 | digitalcommons.library.tmc.edu | Ying Lin |John Steele |Julia Enterria-Rosales |Ramiro A Villarreal-Leal

BACKGROUND: Mesenchymal stem cells (MSCs) derived from gestational tissues offer a promising avenue for prenatal intervention in congenital malformations although their application is hampered by concerns related to cellular plasticity and the need for invasive, high-risk surgical procedures. Here, we present naturally occurring exosomes (EXOs) isolated from amniotic fluid-derived MSCs (AF-MSCs) and their mimetic analogs (MIMs) as viable, reproducible, and stable alternatives.