Julia Tevini

3 weeks ago | nature.com | Elisa Redl |Daniela Weber |Julia Tevini |Barbara Kofler

AbstractAging is a key risk factor for many diseases, including cancer, and a better understanding of its underlying molecular mechanisms may help to prevent, delay, or treat age-related pathologies. Epigenetic alterations such as DNA methylation (DNAme) changes are a hallmark of aging and form the basis of so-called epigenetic clocks, yet their functional relevance and directionality in different organs during disease development is often unclear.

Jul 16, 2024 | pubs.rsc.org | Sepideh Aminzadeh-Gohari |Daniela Weber |Luca Catalano |Julia Tevini

A validated HPLC-MS/MS method for the quantification of systemic mifepristone after subcutaneous application in mice Mifepristone (RU486, MIF) is a synthetic steroidal hormone with progesterone and glucocorticoid receptor antagonistic characteristics. MIF is commonly used for pharmalogical abortions, but also for the treatment of endometrial and endocrine disorders.