Julian Nüchel

Apr 23, 2024 | nature.com | Ishier Raote |Marina Cunquero |Julian Nüchel |Ravi Kiran |Carlo Carolis |Jordi Andilla | +10 more

AbstractUncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies are lacking. A promising approach would be to limit the amount of collagen released from hyperactive fibroblasts.