Julijana Gjorgjieva

Oct 22, 2024 | nature.com | Joel Bauer |Uwe Lewin |Elizabeth Herbert |Julijana Gjorgjieva |Carl Schoonover |Tobias Rose | +1 more

AbstractRepresentational drift—the gradual continuous change of neuronal representations—has been observed across many brain areas. It is unclear whether drift is caused by synaptic plasticity elicited by sensory experience, or by the intrinsic volatility of synapses. Here, using chronic two-photon calcium imaging in primary visual cortex of female mice, we find that the preferred stimulus orientation of individual neurons slowly drifts over the course of weeks.