Junle Qu

Oct 20, 2024 | nature.com | Junle Qu

AbstractFluorescence lifetime imaging microscopy (FLIM) provides quantitative readouts of biochemical microenvironments, holding great promise for biomedical imaging. However, conventional FLIM relies on slow photon counting routines to accumulate sufficient photon statistics, restricting acquisition speeds. Here we demonstrate SparseFLIM, an intelligent paradigm for achieving high-fidelity FLIM reconstruction from sparse photon measurements.

Mar 11, 2024 | opg.optica.org | Rong Xu |Junle Qu |Chenshuang Zhang |Danying Lin

Polarization-resolved second-harmonic generation (PSHG) microscopy is widely used in investigating the structural and morphological alterations of collagen. However, the resolution of second-harmonic generation (SHG) imaging remains constrained by optical diffraction, resulting in the polarization extraction of collagen characteristics from the average properties of collagen fibers.

Jun 10, 2023 | opg.optica.org | Lin Chen |Chao Du |Jun He |Junle Qu

AbstractAn optical fiber φ-OFDR shape sensor with a submillimeter spatial resolution of 200 µm was demonstrated by using femtosecond-laser-induced permanent scatter array (PS array) multicore fiber (MCF). A PS array was successfully inscribed in each slightly twisted core of the 400-mm-long MCF.