Junmei Lu

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Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

Dec 6, 2024 | cell.com | Mengyu Xia |Junmei Lu |Jiabin Lan |Rani Shiao |Hongbin Sun |Zheyu Jin | +14 more

Keywordsinterleukin-22psychological stressseptal neuronsgut leakageTH17anxietydepressionthe septal areaIntroductionPsychological stress is a major etiological inducer of mood disorders such as anxiety disorders and depression. Stress-related psychological diseases impact about 10% of the world population, but prevalence also increases sharply during difficult times such as the COVID-19 pandemic, according to the World Health Organization.

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