Jurjan Aman

Dec 20, 2024 | science.org | Justin Joachim |Davide Maselli |Jurjan Aman |Pamela Swiatlowska |David Killock |Hiba Chaudhry | +10 more

MATERIALS AND METHODS Anti–p-ERM/anti–p-Dmoesin (Cell Signaling Technology, 3141), anti-GST (ChromoTek, 6G9), anti–p-Thr (Cell Signaling Technology, 9381), anti-GFP for Western blotting (ChromoTek, 3H9), anti-GFP for immunofluorescence detection of YFP-TNIK (Roche, 11814460001), anti-TNIK (Santa Cruz Biotechnology, sc-136103), anti-Actin (Sigma-Aldrich, A2228), anti–p-MLC2 Ser19 (Cell Signaling Technology, 3671), anti-Ezrin (Cell Signaling Technology, 3145), anti-moesin (Cell Signaling...

Sep 22, 2024 | biorxiv.org | Jose Gomez-Arroyo |Arjan C. Houweling |Harm J Bogaard |Jurjan Aman

AbstractRationale: Approximately 80% of patients with non-familial pulmonary arterial hypertension (PAH) lack identifiable pathogenic genetic variants. While most genetic studies of PAH have focused on predicted loss-of-function variants, recent approaches have identified ultra-rare missense variants associated with the disease. FOXF1 encodes a highly conserved transcription factor, essential for angiogenesis and vasculogenesis in human and mouse lungs.

Feb 14, 2024 | mdpi.com | Siebe G Blok |Jurjan Aman |Amne Mousa |Dian Karssen

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