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1 week ago | 
healio.com | Justin Cooper |Shenaz Bagha
Research into Sjögren’s disease — both analyzing the condition itself and testing potential treatments — has come a long way in the past decade. “Fifteen years ago, we had no clinical trials, no pharma interest in Sjögren’s, and we were starting to see lupus trials fail one after the other,” Kathy M. Hammitt, vice president of medical and scientific affairs at the Sjögren’s Foundation, told Healio.
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1 week ago | 
healio.com | Justin Cooper |Christine Klimanskis
Key takeaways:Deseyne lenses are embedded with bioactive substances that are gradually released to improve hydration. The lenses will be available for myopia, hyperopia and astigmatism. The FDA approved the Deseyne daily disposable contact lens, which steadily releases bioactive substances that improve hydration and aid comfort, according to a press release from Bruno Vision Care. Paul M.
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1 week ago | 
healio.com | Justin Cooper
Key takeaways:Visual impairment is highly prevalent in long-term care. Older people may view vision deterioration as “inevitable and irreversible.”Vision screening and eye care for residents of long-term care facilities have significant potential to enhance quality of life, but there are barriers to care in these communities, according to a review.
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1 week ago | 
healio.com | Justin Cooper |Shenaz Bagha
Read more Key takeaways:Patients misdiagnosed as psychosomatic/psychiatric reported long-term distrust in clinicians and reduced mental health and self-worth. Past misdiagnoses should be discussed and empathized with. Long-term impacts to mental health and trust in health care providers can result from the misdiagnosis of rheumatic diseases as psychosomatic or psychiatric conditions, according to data published in Rheumatology.
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2 weeks ago | 
healio.com | Justin Cooper
Key takeaways:Sotyktu significantly improved skin and joint symptoms of psoriatic arthritis and reduced patient-reported disability with no new safety signals. The drug is a first-in-class oral TYK2 inhibitor. Sotyktu significantly outperformed placebo for the treatment of psoriatic arthritis in a phase 3 trial, meeting key endpoints at 16 weeks, according to late-breaking data presented at the American Academy of Dermatology annual meeting.
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2 weeks ago | 
healio.com | Justin Cooper
Key takeaways:Older age and Black race increased risk for COVID-19 hospitalization, as did use of glucocorticoids and CD20 blockers. Vaccination 3 to 6 months prior to infection significantly lowered hospitalization risk. Among patients with systemic autoimmune rheumatic diseases, hospitalization due to COVID-19 was more than twice as likely in those using glucocorticoids or CD20 inhibitors, according to data published in RMD Open.
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2 weeks ago | 
healio.com | Justin Cooper
Key takeaways:Among patients with rheumatoid arthritis, major adverse events from biologic/targeted synthetic DMARDs fell by about 25% in the years after market entry. This could be due to the drugs initially being prescribed for more severe disease. Adverse events from disease-modifying antirheumatic drugs for the treatment of rheumatoid arthritis decline by as much as 25% after the drugs are established on the market, according to data published in Annals of the Rheumatic Diseases.
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2 weeks ago | 
healio.com | Justin Cooper
The FDA on Thursday gave the green light to Uplizna in IgG4-related disease, making it the first and only approved treatment for the rare and recently recognized autoimmune condition, according to the drug’s manufacturer. The approval follows the FDA bestowing Uplizna (inebilizumab-cdon, Amgen) its breakthrough therapy designation in August.
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3 weeks ago | 
healio.com | Justin Cooper |Shenaz Bagha
Key takeaways:In patients with lupus, those taking prednisone or demonstrating active disease and a more recent initial episode are more likely to have pericarditis recurrence. Overall recurrence was lower than in the general population. Pericarditis recurrence in lupus is more likely — and has a dose-dependent relationship — with oral prednisone treatment, though overall it is lower than in the general population, according to data published in JAMA Network Open.
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3 weeks ago | 
healio.com | Justin Cooper |Shenaz Bagha
Key takeaways:Patients with asthma had an increased risk for OA, especially among those socially isolated. Stress and altered immune responses could drive inflammation in asthma and OA, researchers hypothesized. Patients with asthma demonstrate a heightened risk for developing osteoarthritis, a relationship that is particularly pronounced when combined with social isolation or loneliness, according to data published in Arthritis Research & Therapy.
