Justin H Lipner

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Comprehensive Characterization of BTK Inhibitor Specificity, Potency, and Biological Effects: Insights into Covalent and Non-covalent Mechanistic Signatures

Sep 8, 2024 | biorxiv.org | Andrew Hanna |Alastair King |Antonia C Darragh |Justin H Lipner

AbstractUncovering a drug's mechanism of action and possible adverse effects are critical components in drug discovery and development. Moreover, it provides evidence for why some drugs prove more effective than others, and how to design better drugs altogether.

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