Justyna K. Hinchcliffe

1 week ago | biorxiv.org | Jennifer Davies |Megan Jackson |Justyna K. Hinchcliffe |Michael Mendl

AbstractAround the world, guidance for the management of laboratory mice recommends social housing (1-3). However, fighting in male mice represents a major animal welfare and scientific issue. Despite the risks of stress and injury and associated welfare costs of in-cage aggression, we currently prioritise group housing. In this study we first validated a trans-species behavioural biomarker of affective state for mice using a chronic corticosterone model of depression.