Kabirullah Lutfy

Feb 23, 2023 | mdpi.com | Asif Iqbal |Abdul Rahim Hamid |Syed Ahmad |Kabirullah Lutfy

Abstract:Excessive high fat diet (HFD) consumption can induce food addiction, which is believed to involve the communication between the hypothalamus and mesolimbic dopaminergic neurons, originating in the ventral tegmental area (VTA) and projecting to the nucleus accumbens (NAc). These brain areas are densely populated with opioid receptors, raising the possibility that these receptors, and particularly mu opioid receptors (MORs), are involved in rewards elicited by palatable food.

Feb 17, 2023 | frontiersin.org | De la Rosa |Ana Maria |Francesco Paolo |Kabirullah Lutfy

1 IntroductionMethylone (3,4-methylenedioxy-N-methylcathinone), also known as MDMC, βk-MDMA, or M1, is a synthetic cathinone that emerged in 2004 as a new psychoactive substance (NPS), although first synthesized in 1996 and planned for therapeutic use as an antidepressant and potential treatment for the Parkinson’s disease (Bossong et al., 2005).