Kaichao Wang

Jun 17, 2024 | chemistry-europe.onlinelibrary.wiley.com | Kaichao Wang |Tiannan Liu |Hang Zhao |Jiang Liu

Introduction Isoguanosine (isoG), an isomer of guanosine (G), has amino and carbonyl groups transposed relative to G. Cherbulize and Bernhard1 originally isolated isoG from croton beans, and Davoll2 subsequently synthesized it. It is widely applied in ionophores, genetics, gel formation, and cancer therapy based on its unique structure and base-pairing pattern (Figure 1).