Kaili Ma

Sep 2, 2024 | mdpi.com | RUI ZHU |Kaili Ma |Xiyu Chen |Jingjing Zhao

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May 27, 2024 | nature.com | Kaili Ma

AbstractImproved vaccination requires better delivery of antigens and activation of the natural immune response. Here we report a lipid nanoparticle system with the capacity to carry antigens, including mRNA and proteins, which is formed into a virus-like structure by surface decoration with spike proteins, demonstrating application against SARS-CoV-2 variants.

Mar 5, 2024 | cell.com | Yue Xu |Kaili Ma |Lianjun Zhang

Lactate influences the behavior of various immune cell types. In a recent Nature Immunology study, Ma et al. revealed that lithium carbonate induces monocarboxylate transporter 1 translocation to mitochondria, enhancing cytoplasmic lactate transport into the mitochondria and increasing lactate mitochondrial metabolism, thereby promoting T cell effector function.