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2 months ago | 
medicalxpress.com | Karl Landsteiner
A study in the journal Pharmaceuticals has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These mutations significantly reduce the proteins' membrane expression and synaptic targeting but do not impair calcium channel activity or trans-synaptic signaling.
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Jan 15, 2025 | 
medicalxpress.com | Karl Landsteiner
Birch pollen allergy is one of the most common allergies in Europe and affects around 450,000 people in Austria alone. It considerably impairs the quality of life and can lead to chronic diseases such as asthma in the long term. Despite this significance, little was previously known about the activity of genes that are directly linked to allergic reactions in the nasal mucosa.
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Dec 27, 2024 | 
mdpi.com | Karl Landsteiner
Share and Cite MDPI and ACS Style Areán, D.; Garcia-Fariña, D.; Landsteiner, K. Strongly Coupled 𝒫𝒯-Symmetric Models in Holography. Entropy 2025, 27, 13. https://doi.org/10.3390/e27010013 AMA Style Areán D, Garcia-Fariña D, Landsteiner K. Strongly Coupled 𝒫𝒯-Symmetric Models in Holography. Entropy. 2025; 27(1):13. https://doi.org/10.3390/e27010013 Chicago/Turabian Style Areán, Daniel, David Garcia-Fariña, and Karl Landsteiner. 2025.
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Nov 29, 2024 | 
phys.org | Karl Landsteiner
Researchers at Karl Landsteiner University of Health Sciences (KL Krems) and ICC Water & Health have developed a new, integrative methodology that enables precise detection of small-scale fecal discharges from inland waterway vessels in flowing waters.
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Nov 29, 2024 | 
azocleantech.com | Karl Landsteiner
Researchers at Karl Landsteiner University of Health Sciences (KL Krems) and ICC Water & Health have achieved a global breakthrough: A new, integrative methodology now enables precise detection of small-scale faecal discharges from inland waterway vessels in flowing waters.
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Nov 20, 2024 | 
medicalxpress.com | Karl Landsteiner
A recent study has uncovered the intricate ways in which a rare genetic mutation impacts brain cell communication, providing critical insights into the causes of a severe neurological disorder known as developmental and epileptic encephalopathy (DEE). The findings reveal that this specific mutation in a regulatory calcium channel subunit disrupts both the calcium handling and structural connections of brain cells, expanding our understanding of how certain neurological conditions may arise.
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Nov 6, 2024 | 
bmcpublichealth.biomedcentral.com | Karl Landsteiner
A total of 30 GPs participated in the study. Participants were recruited from eight of the nine Austrian provinces (all except Salzburg) (Table 1). The gender distribution was well balanced, and we included all three types of general practice in Austria. Details are given in Table 1. During the interviews on managing COVID-19 in their daily work, the GPs almost never (except for one Interview partner, I12) talked about Long-COVID without being explicitly asked about it.
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Oct 16, 2024 | 
medicalxpress.com | Karl Landsteiner
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:The simultaneous inhibition of the transcription factors Myc and JunB could represent a pioneering therapeutic option for the treatment of multiple myeloma (MM), the second most common type of blood cancer.
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Sep 25, 2024 | 
medicalxpress.com | Karl Landsteiner
This article has been reviewed according to Science X's editorial process and policies . Editors have highlighted the following attributes while ensuring the content's credibility:In Europe, incidences of severe native valvular heart disease (VHD) and their treatment vary between men and women. This is the key finding of a comprehensive study conducted at more than 200 centers across Europe.
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Jul 16, 2024 | 
medicalxpress.com | Karl Landsteiner
The protein STAT3 helps the immune system to recognize leukemic cells. This interaction, which is important for future immunotherapies, is now understood in detail thanks to a study at the Karl Landsteiner University of Health Sciences (KL Krems). The study showed that STAT3 influences the formation of surface structures on leukemic cells that make them vulnerable to the immune system. If these structures are missing, leukemic cells can escape the body's innate immune surveillance.
