Kate Chandler

Jan 10, 2025 | cell.com | Ivan K. Chinn |Jonathan May |Anu Goenka |Kate Chandler |Jennifer E. Posey |Alexandra Afenjar | +88 more

Keywords BCL11B C2H2-type zinc finger protein recognition code genotype-phenotype correlation type 2 innate lymphoid cells Introduction Proteins containing a Cys2-His2 zinc-finger domain (C2H2-ZnF) constitute the largest class of human transcription factors.1 They act by either repressing or activating the expression of target genes through binding a specific DNA sequence by their tandem and modular C2H2-ZnFs. Each C2H2-ZnF shares a consensus sequence that folds in the presence of zinc (Zn2+)...

Jan 10, 2025 | cell.com | Ivan K. Chinn |Jonathan May |Anu Goenka |Kate Chandler |Jennifer E. Posey |Alexandra Afenjar | +88 more

Keywords BCL11B C2H2-type zinc finger protein recognition code genotype-phenotype correlation type 2 innate lymphoid cells Introduction Proteins containing a Cys2-His2 zinc-finger domain (C2H2-ZnF) constitute the largest class of human transcription factors.1 They act by either repressing or activating the expression of target genes through binding a specific DNA sequence by their tandem and modular C2H2-ZnFs. Each C2H2-ZnF shares a consensus sequence that folds in the presence of zinc (Zn2+)...

Feb 28, 2024 | declassified.live | Kate Chandler

The high-stakes prosecution of President Donald Trump and several of his associates in Georgia is now mired in controversy following the revelation of a secret love affair between Fulton County District Attorney Fani Willis, who brought the indictment last year, and Nathan Wade, the special prosecutor she appointed to oversee the case. The scandal now represents a potentially fatal blow to what many observers considered the strongest criminal case against the former president.

Jan 23, 2024 | open.substack.com | Kate Chandler

Last week, critical issues surrounding Georgia’s voting system came to the surface in the Curling v. Raffensperger trial in Atlanta. Dr. J. Alex Halderman, a computer science professor at the University of Michigan, revealed how easily Dominion voting systems could be compromised.