Katerina Kachler

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Regulatory eosinophils induce the resolution of experimental arthritis and appear in remission state of human rheumatoid arthritis

1 week ago | fis.tu-dresden.de | Darja Andreev |Mengdan Liu |Katerina Kachler |Mireia Llerins Perez

OBJECTIVES: Eosinophils possess pro-inflammatory functions in asthma. However, our recent studies have suggested that innate lymphoid cells type 2 (ILC2s) and eosinophils have proresolving properties in rheumatoid arthritis (RA). Nothing is known yet about the mechanisms determining the double-edged role of eosinophils. Therefore, we investigated whether asthma, a paradigm eosinophilic disease, can elicit resolution of chronic arthritis.

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