Katrinka M Kocha

Sep 24, 2024 | biorxiv.org | Emilio E Méndez-Olivos |Katrinka M Kocha |Shan Liao |Peng Huang

AbstractIn vertebrates, the sclerotome is a transient embryonic structure that gives rise to various tissue support cells, including fibroblasts. However, how fibroblast precursors are guided to diverse tissues remain poorly understood. Using zebrafish, our lab has previously shown that sclerotome-derived cells undergo extensive migration to generate distinct fibroblasts subtypes, including tenocytes along the myotendinous junction and fin mesenchymal cells in the fin fold.