Kehao Liu

Feb 13, 2024 | onlinelibrary.wiley.com | Danfeng Shen |Qi Huang |Kamoran Tuerhong |Kehao Liu

Using network pharmacology and experimental validation to explore the therapeutic efficacy and mechanism of curcumin (Cur) in periodontitis treatment. Network pharmacology was utilized to predict target gene interactions of Cur-Periodontitis. Molecular docking was used to investigate the binding affinity of Cur for the predicted targets. A mouse model with ligature-induced periodontitis (LIP) was used to verify the therapeutic effect of Cur.