Kenneth D. Carr

Oct 22, 2024 | biorxiv.org | Sanela Rankovic |Kenneth D. Carr |Justin Decarreau |Rebecca Skotheim

AbstractRecent advances in computational methods have led to considerable progress in the design of self-assembling protein nanoparticles. However, nearly all nanoparticles designed to date exhibit strict point group symmetry, with each subunit occupying an identical, symmetrically related environment. This property limits the structural diversity that can be achieved and precludes anisotropic functionalization.