Kevin K. Tsia

Jul 30, 2024 | pubs.rsc.org | Pokfulam Road |New Territories |Kevin K. Tsia

Dispersion-free inertial focusing (DIF) for high-yield polydisperse micro-particle filtration and analysis† Inertial focusing excels at the precise spatial ordering and separation of microparticles by size within fluid flows.

Jun 12, 2024 | onlinelibrary.wiley.com | Kevin K. Tsia

1 Introduction Recent breakthroughs in label-free single-cell imaging have highlighted the significance of biophysical cytometry in understanding functional cellular heterogeneity in complex biological systems.[1] Supercharged by their increasing throughput and content, systematic profiling of biophysical cell morphology, which was once inconceivable, is now feasible to probe subtle differences in cell mass, shape, size, and biophysical/mechanical properties across different cell types/states...

Jan 23, 2024 | biorxiv.org | Kevin K. Tsia

AbstractInertial focusing excels at the precise spatial ordering and separation of microparticles by size within fluid flows. However, this advantage, brought by its inherent size-dependent dispersion, could turn into a drawback that challenges applications requiring consistent and uniform positioning of polydisperse particles, such as microfiltration and flow cytometry. To overcome this fundamental challenge, we introduce Dispersion-Free Inertial Focusing (DIF).