Kirk M Druey

Nov 13, 2024 | nature.com | Kirk M Druey |Laurent Arnaud |Samir Parikh

AbstractThe vascular endothelial barrier maintains intravascular volume and metabolic homeostasis. Although plasma fluids and proteins extravasate continuously from tissue microvasculature (capillaries, post-capillary venules), systemic vascular leakage increases in critical illness associated with sepsis, burns and trauma, among others, or in association with certain drugs or toxin exposures.