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3 weeks ago | 
scopeblog.stanford.edu | Mark Conley |Krista Conger
Ozempic and similar semaglutide-based medications have been hailed as miracle drugs. Known as GLP-1 (glucagon-like peptide-1) agonists, this class of medications mimics a natural hormone the small intestine releases after you eat. They slow the movement of food through the gut and boost insulin production, increasing the feeling of fullness and suppressing appetite.
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Jan 12, 2025 | 
med.stanford.edu | Krista Conger
After completing a doctorate in biology at Harvard followed by a postdoctoral position at the University of California, San Francisco, Blau arrived at Stanford University in 1978 as an assistant professor of pharmacology in the School of Medicine - becoming one of the first women to be hired on the tenure track in the basic sciences. (The other was Carla Shatz, PhD, professor of biology and of neurobiology and the Sapp Family Provostial Professor.
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Jan 8, 2025 | 
medicalxpress.com | Krista Conger
The melding of visual information (microscopic and X-ray images, CT and MRI scans, for example) with text (exam notes, communications between physicians of varying specialties) is a key component of cancer care. But while artificial intelligence helps doctors review images and home in on disease-associated anomalies like abnormally shaped cells, it's been difficult to develop computerized models that can incorporate multiple types of data.
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Jan 8, 2025 | 
med.stanford.edu | Krista Conger
"The biggest unmet clinical need is for models that physicians can use to guide patient treatment," Li said. "Does this patient need this drug? Or should we instead focus on another type of therapy?
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Nov 14, 2024 | 
scopeblog.stanford.edu | Krista Conger
It takes mere minutes to calculate your body mass index, more commonly known as BMI, by using your height and weight. With countless online charts, you can find out not only what your BMI is, but which of its categorical classifications you fall into: underweight, normal, overweight or obese. For decades, BMI has been used to stratify people for research and clinical care.
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Nov 7, 2024 | 
med.stanford.edu | Krista Conger
The researchers also showed that the circles can contain not just cancer-driving oncogenes and genes that modulate the immune response, but also that others can contain only DNA sequences called enhancers that drive the expression of genes on other circles by linking two or more ecDNAs together. "This was kind of a heretical idea," Chang said. "The ecDNAs with enhancer elements don't confer any benefit to the cell on their own; they have to work with other ecDNAs to spur cancer cell growth.
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Oct 16, 2024 | 
scopeblog.stanford.edu | Margarita Gallardo |Mark Conley |Krista Conger
In his nearly two decades as a clinical professor at Stanford Medicine, Bryant Lin had never stood before a classroom of students as a patient -- let alone as a patient who, despite never inhaling "a single puff of smoke of any kind," has been afflicted with an incurable form of late-stage lung cancer. Therefore, it was little surprise when the focus of lesson No. 1 in his new fall class swerved toward Lin's tear ducts rather than his lungs. "I was hoping not to get choked up...
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Sep 30, 2024 | 
med.stanford.edu | Krista Conger
Structured attempts to change an LGBTQIA+ person's sexual orientation or gender identity - a practice commonly called "conversion therapy" - is linked to greater symptoms of depression, post-traumatic stress disorder and suicidality, according to a study led by Stanford Medicine researchers.
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Sep 12, 2024 | 
scopeblog.stanford.edu | Jamie Hansen |Nina Bai |Krista Conger |Nina BaiPublished
Mpox has returned as a significant global health concern in recent months. A relative of smallpox, mpox (formerly called monkeypox) has circulated in Central and West African countries for decades. In the last few years, a new offshoot of the virus emerged which spread more readily through close person-to-person contact.
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Aug 23, 2024 | 
stanmed.stanford.edu | Krista Conger
Arguably every cell in your body matters, but which are the most interesting? The most mysterious, surprising or - yes- even the prettiest? These might seem impossible questions to answer, but when we asked several Stanford Medicine scientists to name their favorite cell and explain why, answers came easily - and ran the gamut. With some creative license, we found that each of the cells listed could be assigned a range of attributes not out of place in a high school yearbook.
