Kyeezu Kim

Jun 12, 2023 | jamanetwork.com | Kyeezu Kim |Kristine Yaffe |David H. Rehkopf

Key PointsQuestion  Do individuals with adverse childhood experiences (ACEs) have accelerated epigenetic age in their midlife? Findings  In this cohort study of 895 adults at year 15 and 867 adults at year 20 of follow-up with DNA methylation profiling, participants with 4 or more ACEs were likely to have older epigenetic ages compared with their chronological ages independently of their socioeconomic status in early or later life.