Kylie R. James

Jan 30, 2024 | nature.com | Kylie R. James

When considering intestinal biology, one can draw uncanny parallels to the rolling hills of the Tuscan countryside, defined by gradual undulations of the land, scattered with vineyards of the old world. Tuscan hills and valleys maximize the surface area of the land and provide variation in the ecosystem to support the diversity of wine produced in such a small space. The villi and crypts of the small intestines provide the large surface area required for nutrient absorption.

May 31, 2023 | nature.com | Matthias Zilbauer |Kylie R. James |Mandeep Kaur |Sebastian Pott |Zhixin Li |Jay R. Thiagarajah | +20 more

AbstractThe number of studies investigating the human gastrointestinal tract using various single-cell profiling methods has increased substantially in the past few years. Although this increase provides a unique opportunity for the generation of the first comprehensive Human Gut Cell Atlas (HGCA), there remains a range of major challenges ahead.