Kyndal A Schade

4 weeks ago | biorxiv.org | Lauren Dunn |Brian F Niemeyer |Neetha P Eduthan |Kyndal A Schade

AbstractTrisomy 21 (T21) gives rise to Down syndrome (DS), the most commonly occurring chromosomal abnormality in humans. T21 affects nearly every organ and tissue system in the body, predisposing individuals with DS to congenital heart defects, autoimmunity, and Alzheimer's disease, among other co-occurring conditions.