Lan Ma

Jan 16, 2025 | biorxiv.org | Yanghui Xiang |Xu Dong |Lan Ma |Dan Cao

AbstractBackground: The genus Providencia includes species of ecological and clinical significance, with some acting as opportunistic pathogens in hospital-acquired infections such as urinary tract infection (UTI). However, overlapping phenotypic traits and genetic similarities pose challenges for accurate species characterization. This study exemplifies this challenge by identifying a novel Providencia isolate through genomic analysis.

Dec 12, 2024 | mdpi.com | Lan Ma

1. IntroductionThe incidence of nasopharyngeal carcinoma (NPC) exhibits a high prevalence in the southern regions of China [1]. Although Epstein–Barr Virus (EBV) antibody and EBV DNA testing can significantly improve the diagnosis of NPC, non-invasive screening using them alone may still lead to underdiagnosis with unsatisfactory clinical reliability [2,3]. Therefore, the development of new screening mechanisms for NPC holds significant value.

Oct 5, 2024 | nature.com | Weihao Gao |Fuju Rong |Lei Shao |Zhuo Deng |Chucheng Chen |Zheng Gong | +6 more

The electronic medical record management system plays a crucial role in clinical practice, optimizing the recording and management of healthcare data. To enhance the functionality of the medical record management system, this paper develops a customized schema designed for ophthalmic diseases. A multi-modal knowledge graph is constructed, which is built upon expert-reviewed and de-identified real-world ophthalmology medical data. Based on this data, we propose an auxiliary diagnostic model based on a contrastive graph attention network (CGAT-ADM), which uses the patient’s diagnostic results as anchor points and achieves auxiliary medical record diagnosis services through graph clustering. By implementing contrastive methods and feature fusion of node types, text, and numerical information in medical records, the CGAT-ADM model achieved an average precision of 0.8563 for the top 20 similar case retrievals, indicating high performance in identifying analogous diagnoses. Our research findings suggest that medical record management systems underpinned by multimodal knowledge graphs significantly enhance the development of AI services. These systems offer a range of benefits, from facilitating assisted diagnosis and addressing similar patient inquiries to delving into potential case connections and disease patterns. This comprehensive approach empowers healthcare professionals to garner deeper insights and make well-informed decisions.

Aug 27, 2024 | dx.doi.org | Lan Ma |Honghui Wu |Jian Cao |Nan Zhang

Biological and Medical Applications of Materials and InterfacesAugust 27, 2024 Lan Ma State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China College of Pharmacy, Inner Mongolia Medical University, Chilechuan Dairy Economic Development Zone, Hohhot, Inner Mongolia Autonomous Region 010110, China Honghui Wu State Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical...

Oct 12, 2023 | agupubs.onlinelibrary.wiley.com | Yong Gu Ji |Lan Ma |Chao Shen |Gang Zeng

1 Introduction SYM-H index is a geomagnetic index introduced to describe the strength of geomagnetic storms (Mayaud, 1980). It is determined by the 1-min average of the horizontal component of the geomagnetic disturbance measured by several ground stations located near the equatorial regions with low latitude, which is similar to Dst index with 1 hr resolution (Wanliss & Showalter, 2006).