Landon J. Kilgallon

Mar 18, 2024 | pubs.rsc.org | Bin Liu |Jacob Rodriguez |Landon J. Kilgallon |Wencong Wang

An organometallic swap strategy for bottlebrush polymer–protein conjugate synthesis† Polymer–protein bioconjugation offers a powerful strategy to alter the physical properties of proteins, and various synthetic polymer compositions and architectures have been investigated for this purpose.

Aug 3, 2023 | pubs.acs.org | Landon J. Kilgallon |Yang Shao-Horn |Jeremiah Johnson

A simple, scalable synthetic methodology for the synthesis of N,N-dimethyltrifluoromethanesulfonamide (DMTMSA) and other trifluoromethanesulfonamide solvents is described. No specialized glassware is required, water is the solvent, and an ice bath is used for cooling. Up to 155 g of DMTMSA is synthesized in a single batch in 92% yield.