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4 days ago | 
insideprecisionmedicine.com | Larissa Warneck-Silvestrin |Larissa Warneck
GLP-1RAs, first-generation weight-loss medications, such as liraglutide—known by the brand names Victoza and Saxenda—and exenatide—marketed under the names Byetta and Bydureon—seem to have anti-cancer benefits beyond weight loss, compared to weight loss surgery. This new study was led by researchers of Clalit Health Services in Tel Aviv, Israel, and the Hasharon Hospital, Rabin Medical Center in Petah Tikva, Israel.
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Nov 22, 2024 | 
insideprecisionmedicine.com | Larissa Warneck-Silvestrin |Larissa Warneck
Researchers at Fudan University in Shanghai, China, have created an atlas of the human plasma proteome based on data from over 53,000 adults. This data can enable precision medicine by helping researchers understand which proteins are linked to diseases and which are health-related. The study was recently published in the journal Cell. Using data from the UK Biobank, the researchers associated 2,920 plasma proteins with 406 prevalent diseases, 660 incident diseases, and 986 health-related traits.
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Nov 21, 2024 | 
insideprecisionmedicine.com | Larissa Warneck-Silvestrin |Larissa Warneck
The field of molecular diagnostics—also known as molecular pathology—is experiencing a period of rapid growth. In 2023, the global molecular diagnostics market size was valued at around $15.4 billion, reaching an estimated $17.3 billion in 2024, and is expected to grow at a CAGR of 13.5% by 2029 to reach $32.7 billion.
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Nov 13, 2024 | 
insideprecisionmedicine.com | Larissa Warneck-Silvestrin |Larissa Warneck
Researchers at the Georgia Institute of Technology have developed lab-grown models of the human immune system that can be used to understand why some cancer patients are more susceptible to frequent infections even years after completing cancer treatment. Known as human immune organoids, these miniature models of the human immune system address two key challenges for researchers and patients.
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May 29, 2024 | 
insideprecisionmedicine.com | Larissa Warneck
Researchers at the University College London (UCL) and UCL Great Ormond Street Institute of Child Health have developed a novel immunotherapeutic platform technology that uses engineered T cells to attack bone cancer cells and activate other cancer-fighting immune cells to do the same. The researchers aimed to overcome different challenges that current immunotherapies have in treating solid tumors.
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May 3, 2024 | 
insideprecisionmedicine.com | Larissa Warneck
Researchers at the Medical College of Georgia (MCG) have found that targeting a specific receptor in the eye may benefit many patients with neovascular age-related macular degeneration, who don’t respond well to current treatments. Age-related macular degeneration is a leading cause of blindness worldwide and occurs mostly in the elderly and people with metabolic diseases, such as diabetes and obesity.
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May 2, 2024 | 
insideprecisionmedicine.com | Larissa Warneck
Researchers at the University of California, Los Angeles (UCLA) have discovered that a known network of inflammatory molecules could be used as biomarkers to calculate a person’s risk of developing cerebral small vessel disease, a common cause of stroke and cognitive decline. In current clinical practice, the only way to understand a person’s susceptibility to developing cerebral small vessel disease is a combination of medical imaging techniques, family history, and assessing other risk factors.
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May 1, 2024 | 
insideprecisionmedicine.com | Larissa Warneck
A team of researchers from around the world, who are part of the International Consortium of Blood Pressure, have discovered more than 100 new regions in the human genome that seem to influence a person’s blood pressure. These findings enabled the researchers to improve polygenic risk scores to be more predictive of blood pressure and hypertension risk. Approximately 1.28 billion adults worldwide have high blood pressure, also known as hypertension.
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Apr 30, 2024 | 
insideprecisionmedicine.com | Larissa Warneck
A team of researchers from the Vanderbilt University Medical Center, the Columbia University Irving Medical Center, and the Technical University Munich has found that smooth muscle cells lining the arteries of atherosclerosis patients can develop into other cell types with traits similar to cancer. These findings could pave the way for new ways of preventing and developing treatments for atherosclerosis.
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Apr 29, 2024 | 
insideprecisionmedicine.com | Larissa Warneck
The Human Immunome Project, a global nonprofit scientific initiative, has released its plans to decode and model the human immune system by generating the world’s most diverse and largest immunological dataset to date. Understanding the complexities of the human immune system is essential for developing treatments against different diseases—including cancer, autoimmune, and infectious diseases—and improving humans’ overall health.
