Larry K. Kociolek

Jan 13, 2025 | biorxiv.org | Daniel Paredes-Sabja |Larry K. Kociolek |César Rodríguez |Merilyn A Beebe

AbstractClostridioides difficile infections (CDI) cause almost 300,000 hospitalizations per year of which ~15-30% are the result of recurring infections. The prevalence and persistence of CDI in hospital settings has resulted in an extensive collection of C. difficile clinical isolates and their classification, typically by ribotype.

Jul 4, 2023 | kevinmd.com | Larry K. Kociolek |Dennis Wichern |Yumiko Nakamura |Vishnu Muppala

Carol Raye’s devastating Clostridioides difficile (C. difficile) experience started with what she thought was a stomach bug after a dental visit. She took the antibiotics prescribed by her dentist and thought a weekend of rest would make her feel better. Soon, she was debilitated by the severe diarrhea from a C. difficile infection that left her weak, confused and barely able to get out of bed.