Laura J. Myhill

Feb 6, 2024 | biorxiv.org | Pankaj Arora |Ling Zhu |Laura J. Myhill |Nilay Budeyri Gokgoz

AbstractPolyphenols are phytochemicals commonly found in plant-based diets which have demonstrated immunomodulatory and anti-inflammatory properties. However, the interplay between polyphenols and pathogens at mucosal barrier surfaces has not yet been elucidated in detail. Here, we show that proanthocyanidin (PAC) polyphenols interact with gut parasites to influence immune function and gut microbial-derived metabolites in mice.