Laura Sisalli

Jun 5, 2023 | mdpi.com | Francesco D’Ambrosio |Alessandra Amato |Laura Sisalli |Andrea Chiacchio

4.2. The Influence of Most Important Systemic Diseases and Drugs Evaluated on the Outcomes Considered in This Umbrella Review 4.2.1. Metabolic Bone DiseaseMetabolic bone diseases, such as osteopenia and osteoporosis, are pathologies particularly frequent in the elderly population. Osteoporosis affects more than 200 million individuals worldwide, mainly postmenopausal women. Osteoporosis is a disease that leads to a progressive loss of bone mass, increasing the risk of fractures and bone fragility.