Laure Marignol

Mar 27, 2024 | nature.com | Laure Marignol

AbstractThe Y-box binding protein-1 (YBX1) gene codes for a multifunctional oncoprotein that is increasingly being linked to the regulations of many aspects of cancer cell biology. Disparities in treatment outcomes between male and female cancer patients are increasingly reported. This study aimed to examine the relationship between YBX1 expression and overall survival in male and female patients with solid tumours.

Feb 1, 2024 | bmjoncology.bmj.com | Laure Marignol |Christopher Pugh

Genetic markersSolid tumourTumour biomarkersMultiple lines of evidence confirm the strong association between the presence of hypoxia in solid tumours and poorer outcomes in patients with cancer resulting from both more aggressive tumour cell behaviour and impaired responses to therapy.1 2 With well over 12 000 articles published in the past 5 years alone (source, PubMed), the importance of hypoxia in cancer is indisputable.

May 19, 2023 | pubmed.ncbi.nlm.nih.gov | Laure Marignol

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