Lauren A McKibben

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Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure

Nov 3, 2024 | biorxiv.org | Lauren A McKibben |Meghna Iyer |Ying Zhao |Roxana Florea

AbstractUnfortunately, survivors of traumatic stress exposure (TSE) frequently develop adverse posttraumatic neuropsychiatric sequelae (APNS) such as chronic pain and stress/depressive symptoms. Increasing evidence indicates that there is a 'window of opportunity' following TSE in which therapeutic interventions are most effective against APNS, yet mechanisms accounting for this observation are poorly understood.

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