Lausanne Branch

Jun 11, 2024 | rupress.org | Lausanne Branch |Johanna Chiffelle |Alexandre Harari

In cancer research, antigens have long been recognized as pivotal triggers of immune responses and potential therapeutic targets. Antigens are commonly categorized into tumor-associated antigens (TAAs) or canonical neoantigens (Peri et al., 2023). TAAs are self-antigens, showing varied expression patterns within tumors.

May 30, 2024 | karger.com | Lausanne Branch |Van Schaik

Background: Intravenous immunoglobulin (IVIg) has been used for almost 40 years in the treatment of autoimmune and systemic inflammatory diseases. Numerous cells are involved in the innate immune response, including monocytes/macrophages, neutrophils, dendritic cells, mast cells, basophils, eosinophils, natural killer cells, and innate lymphoid cells. Many studies have investigated the mechanisms by which IVIg down-modulates inflammatory and autoimmune processes of innate immune cells.