Lena M. Müller

Jan 4, 2024 | cell.com | Fernando Contreras |Genevieve M. Auger |Lena M. Müller |Vincent Richter

Highlights•The CG11318 locus encodes the adhesion GPCR mayo•mayo controls midgut size through enterocyte proliferation•mayo removal results in hyperkalemia•Loss of mayo causes tachycardiaSummaryAdhesion G-protein-coupled receptors (aGPCRs) form a large family of cell surface molecules with versatile tasks in organ development. Many aGPCRs still await their functional and pharmacological deorphanization.