Leo Gendelev

Nov 17, 2024 | nature.com | Leo Gendelev |Jack Taylor |Michelle Arkin

AbstractBehavioral larval zebrafish screens leverage a high-throughput small molecule discovery format to find neuroactive molecules relevant to mammalian physiology. We screen a library of 650 central nervous system active compounds in high replicate to train deep metric learning models on zebrafish behavioral profiles. The machine learning initially exploited subtle artifacts in the phenotypic screen, necessitating a complete experimental re-run with rigorous physical well-wise randomization.

Nov 16, 2024 | flipboard.com | Leo Gendelev |Jack Taylor |Douglas Myers-Turnbull |Steven Chen |Michelle Arkin |Michael Keiser | +2 more

11 hours agoCNN — Laken Riley, 22, left home at 9:03 a.m. on February 22 with her iPhone for a February morning jog. She brought her smartwatch and noise-canceling AirPods along for the run. Just 25 minutes later, she was dead. Her house’s Ring camera footage captured Riley, wearing a ponytail and dressed in a …