Leo Meriranta

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Inflammatory and subtype-dependent serum protein signatures predict survival beyond the ctDNA in aggressive B cell lymphomas

Apr 4, 2024 | cell.com | Leo Meriranta |Peter Brown |Kristina Drott |Klaus Beiske

Highlights•Landscape of 1,463 serum proteins in high-risk large B cell lymphoma (LBCL)•Inflamed serum protein profile predicts poor survival in primary LBCL•Several serum proteins complement circulating tumor DNA assessment•Lymphoma subtype marker proteins can be used to estimate response to therapyContext and significanceClinical and biological heterogeneity remains a challenge for improving large B cell lymphoma (LBCL) survival.

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