Levi Gadye

4 weeks ago | ucsf.edu | Levi Gadye

After a storied scientific career that began with the discovery of how hormones control genes, Keith Yamamoto, PhD, has retired. Yamamoto, who most recently served as Vice Chancellor for Science Policy and Strategy at UCSF, is best known for his role in developing the concept of precision medicine, which he laid out in a report along with colleagues at the National Academies of Sciences, Engineering, and Medicine. Precision medicine was just one of his many contributions to science policy.

1 month ago | medicalxpress.com | Levi Gadye

Swirling inside every cell are millions of microscopic messages called messenger RNAs (mRNAs). The messages are the genetic blueprints for proteins, which determine the behavior and health of the cell. All mRNAs are packaged to ensure they're only used at the right place and time—imagine notes sealed in envelopes. But in cancer, enzymes called helicases relentlessly unseal thousands of mRNAs, leading to out-of-control protein production.

1 month ago | ucsf.edu | Levi Gadye

Swirling inside every cell are millions of microscopic messages called messenger RNAs (mRNAs). The messages are the genetic blueprints for proteins, which determine the behavior and health of the cell. All mRNAs are packaged to ensure they’re only used at the right place and time – imagine notes sealed in envelopes. But in cancer, enzymes called helicases relentlessly unseal thousands of mRNAs, leading to out-of-control protein production.

1 month ago | ucsf.edu | Levi Gadye

UCSF researchers may have discovered how the female brain remains resilient in aging, answering an age-old question of how most women outlive men and retain their cognitive abilities longer. Females carry two X chromosomes. One of them is ensconced in a corner in the cell called the Barr body, where it can’t express many genes, and scientists thought it didn’t do much of anything.

1 month ago | ucsf.edu | Laura Kurtzman |Levi Gadye

UC San Francisco received $815 million in awards from the National Institutes of Health (NIH) last year for research that will improve the lives of patients in the U.S. and around the world. The grants enable UCSF scientists to test new treatments for dementia and stroke, investigate the environmental causes of cancer and look for new ways to treat the world’s number one infectious disease killer, tuberculosis, which is becoming increasingly resistant to drugs.