Lifecourse Epidemiology

Nov 18, 2024 | diabetesjournals.org | Lifecourse Epidemiology

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May 2, 2024 | publications.aap.org | Lifecourse Epidemiology

Polycystic Ovary Syndrome (PCOS) is common among females, with significant metabolic and reproductive comorbidities. We describe PCOS development in a pediatric population. We assessed cardiometabolic biomarkers and adiposity at the midchildhood (mean 7.9 y), early teen (mean 13.1 y), and midteen (mean 17.8 y) visits among 417 females in the prospective Project Viva cohort. We defined PCOS via self-reported diagnosis or ovulatory dysfunction with hyperandrogenism in midlate adolescence.

Jan 3, 2024 | publications.aap.org | Lifecourse Epidemiology

Citation Gayle M. Shipp, Adaeze C. Wosu, Emily A. Knapp, Katherine A. Sauder, Dana Dabelea, Wei Perng, Yeyi Zhu, Assiamira Ferrara, Anne L. Dunlop, Sean Deoni, James Gern, Christy Porucznik, Izzuddin M. Aris, Margaret R. Karagas, Sheela Sathyanarayana, Tom G. O’Connor, Kecia N. Carroll, Rosalind J. Wright, Christine W. Hockett, Christine C. Johnson, John D. Meeker, José Cordero, Nigel Paneth, Sarah S. Comstock, Jean M.

Sep 6, 2023 | publications.aap.org | Lifecourse Epidemiology

First, there are certainly larger cohort studies in which to ask questions about maternal body size, early-life growth, and future obesity – including the Millennium Cohort Study. However, these large studies frequently rely on self-reported maternal prepregnancy BMI, which is subject to bias.1 Larger studies may also lack directly-assessed body composition, a main outcome of interest and major strength of our study.

May 18, 2023 | academic.oup.com | Lifecourse Epidemiology

Previous studies have shown that exposure to maternal gestational diabetes mellitus (GDM) is associated with increased offspring body mass index (BMI) and risk for overweight or obesity. This study aimed to explore differences in BMI trajectories among youth exposed or not exposed to maternal GDM and understand whether these associations differ across life stages.