Lin-Xi Wan

May 20, 2024 | onlinelibrary.wiley.com | Yiren Yang |Yi Mou |Lin-Xi Wan |Sichuan province

Supporting Information Filename Description med22057-sup-0001-Summary_Sheet_2_6.docx96.3 KB Supporting information. REFERENCES 1, , , , . Trends in kinase drug discovery: targets, indications and inhibitor design. Nat Rev Drug Disc. 2021; 20: 839-861. 2, , , et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nature Med. 1996; 2(5): 561-566. 3, . Hallmarks of cancer: the next generation. Cell. 2011; 144(5): 646-674.

Dec 5, 2023 | pubs.rsc.org | Zhi Yang |Yu Chen |Lin-Xi Wan |Yuxiao Li

Iridium-catalyzed Asymmetric, Complete Hydrogenation of Pyrimidinium Salts under Batch and Flow A highly enantioselective method for the complete hydrogenation of pyrimidinium salts using Ir/(S,S)-f-Binaphane complex as the catalyst was presented in this study. This approach affords facile access to a range of fullly saturated chiral hexahydropyrimidines, which are prevalent in many bioactive molecules.