Line Christiansen

2 months ago | digitalcommons.library.tmc.edu | Line Christiansen |Gemma Ventura |Bo Holmqvist |Karoline Aasmul-Olsen

KeywordsIGF-1, motor function, preterm neonates, myelination, caudate nucleus, hippocampusAbstractINTRODUCTION: Preterm infants have increased risk of impaired neurodevelopment to which reduced systemic levels of insulin-like growth factor 1 (IGF-1) in the weeks after birth may play a role. Hence, we hypothesized that postnatal IGF-1 supplementation would improve brain development in preterm pigs, used as a model for preterm infants.